Amenhotep II was the son of Thutmose III and a minor wife, Hatshepsut-Meryetre.
His reign is usually dated from 1427 to 1400 BC. Since Thutmose III had devoted so much energy to expanding Karnak, Amenhotep's building projects were largely focused on enlarging smaller temples all over Egypt.
In Nubia, Amenhotep built at Qasr Ibrim and Semna, and ordered the decoration of the Temple at Kalabsha. However, his most famous Nubian temple was at Amada.
Amenhotep did not record the names of his queens; some Egyptologists theorize that he felt that women had become too powerful under titles such as God's Wife of Amun. They point to the fact that he participated in his father's removal of Hatshepsut's name from her monuments and the destruction of her image.